The holiday hangout will go online tomorrow! If there's anything in the regular subforums that you're going to want to access over the holidays, copy it now while it's still accessible.
Our new Indie Games subforum is now open for business in G&T. Go and check it out, you might land a code for a free game. If you're developing an indie game and want to post about it, follow these directions. If you don't, he'll break your legs! Hahaha! Seriously though.
Our rules have been updated and given their own forum. Go and look at them! They are nice, and there may be new ones that you didn't know about! Hooray for rules! Hooray for The System! Hooray for Conforming!
The technology behind the MIT sensor, described in a December 2009 issue of ACS Nano, is fundamentally different from existing sensors, says Strano. The sensor is based on carbon nanotubes wrapped in a polymer that is sensitive to glucose concentrations. When this sensor encounters glucose, the nanotubes fluoresce, which can be detected by shining near-infrared light on them. Measuring the amount of fluorescence reveals the concentration of glucose.
The researchers plan to create an “ink” of these nanoparticles suspended in a saline solution that could be injected under the skin like a tattoo. The “tattoo” would last for a specified length of time, probably six months, before needing to be refreshed.
To get glucose readings, the patient would wear a monitor that shines near-infrared light on the tattoo and detects the resulting fluorescence. One advantage of this type of sensor is that, unlike some fluorescent molecules, carbon nanotubes aren’t destroyed by light exposure. “You can shine the light as long as you want, and the intensity won’t change,” says Barone. Because of this, the sensor can give continuous readings.
Development of the nanoparticles and the wearable monitor is being funded by MIT’s Deshpande Center for Technological Innovation.
Barone and Strano are now working to improve the accuracy of their sensor. Any glucose monitor must pass a test known as the Clarke Error Grid, the gold standard for glucose-sensor accuracy. The test, which compares sensor results to results from a lab-based glucose meter, needs to be very stringent, since mistakes in glucose detection can be fatal.
They are still years away from human trials, says Barone, but they may soon start trials in animals. Those tests will be key to determining the value of this approach, says Buckingham. “You don’t know how good it will be until you put it in someone and see how strong the signal is,” he says.
There's a few people I know whom are living with this stupid fucknut of a disease. Seriously, it's bullfuck. You prick your finger, check your levels, need to pay through the teeth for insulin and your prise is a shorter life span.