Patients receiving Zmapp in the four trial centers experienced an overall mortality rate of 49 percent, according to Anthony Fauci, director of the NIH’s National Institute of Allergy and Infectious Diseases. (Mortality rates are in excess of 75 percent for infected individuals who don’t seek any form of treatment.) The monoclonal antibody cocktail produced by a company called Regeneron Pharmaceuticals had the biggest impact on lowering death rates, down to 29 percent, while NIAID’s monoclonal antibody, called mAb114, had a mortality rate of 34 percent. The results were most striking for patients who received treatments soon after becoming sick, when their viral loads were still low—death rates dropped to 11 percent with mAb114 and just 6 percent with Regeneron’s drug, compared with 24 percent with ZMapp and 33 percent with Remdesivir.
From a 1 in 4 chance at survival to (if treated quickly) a 1 in 10 or 1 in 20 chance at death.
Naturally they're going to charge more for that drug than anyone in regions impacted by Ebola can afford, I wager.
+6
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JedocIn the scupperswith the staggers and jagsRegistered Userregular
edited August 2019
That would actually be very surprising. Medicine in the developing world is nothing like the high-end auction bullshit you get in the US. There's a very limited pool of resources available, and the patients aren't the ones ponying up in most cases. In many parts of the world, if you've got a TB cure that costs a hundred bucks a dose and a malaria cure that costs a dollar a dose, you end up with a drastic reduction in malaria deaths and a bunch of medical professionals who are really good at delivering the bad news to TB patients. The math is terrible, but it's not hard.
In this case, where ebola is a really scary disease that's mostly affecting some of the poorest countries in the world, a cure that's too expensive for WHO and various charitable organizations to roll out on a wide scale might as well not exist. Drug manufacturers know that, and would rather get a whole small pie than a big slice of a pie that doesn't exist.
This is the sort of bleak economic calculus that means you can get a once-in-a-lifetime polio vaccine for 75 cents in Pakistan but you need to pay $25 for your flu vaccine every year in the US.
Life has a price tag, and it's more variable than you might think.
That would actually be very surprising. Medicine in the developing world is nothing like the high-end auction bullshit you get in the US. There's a very limited pool of resources available, and the patients aren't the ones ponying up in most cases. In many parts of the world, if you've got a TB cure that costs a hundred bucks a dose and a malaria cure that costs a dollar a dose, you end up with a drastic reduction in malaria deaths and a bunch of medical professionals who are really good at delivering the bad news to TB patients. The math is terrible, but it's not hard.
In this case, where ebola is a really scary disease that's mostly affecting some of the poorest countries in the world, a cure that's too expensive for WHO and various charitable organizations to roll out on a wide scale might as well not exist. Drug manufacturers know that, and would rather get a whole small pie than a big slice of a pie that doesn't exist.
This is the sort of bleak economic calculus that means you can get a once-in-a-lifetime polio vaccine for 75 cents in Pakistan but you need to pay $25 for your flu vaccine every year in the US.
Life has a price tag, and it's more variable than you might think.
Eat at Arby's.
There's also the fact that if an exposed family wins at lousy timing and starts going symptomatic on a bus in Kinshasa - or Atlanta, for that matter - things would get Very Very Bad. Nipping that sort of thing in the bud in a place where The Invisible Hand(tm) allows it to be affordable isn't just the right thing to do in and of itself, it prevents some pretty catastrophic scenarios that are really a when-not-if sort of thing if they'd tried to roll out a less affordable treatment to make the next shareholders' meeting happier.
(That and, if it got out that a pharmaceutical company let an outbreak get out of control because they weren't willing to keep the treatment affordable, there would probably be blood in the streets that wasn't a direct result of the virus.)
Just when I was coming around to trex being covered in feathers now we think it could fly too?
Haast's Eagle
It lived up until recently +/- 40k years ago as the Maori have legends about them
I cannot find it right now but there is a leathery fossil that was used as either a fetish or weapon during the ice age from haast's eagle
+1
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FishmanPut your goddamned hand in the goddamned Box of Pain.Registered Userregular
Probably not ice age; the Polynesians didn't reach NZ until the 1300's, well after the last Ice Age.
It probably went extinct around the time of the arrival of Europeans, mostly owing to the hunting to extinction of its primary prey, the Moa, by the Maori around that time.
JedocIn the scupperswith the staggers and jagsRegistered Userregular
edited August 2019
Charred grass, at the moment. But generally the soil underneath is pretty well Fulgurized, so that same pattern will show in bare dirt for a while until the grass can reestablish itself.
Probably not ice age; the Polynesians didn't reach NZ until the 1300's, well after the last Ice Age.
It probably went extinct around the time of the arrival of Europeans, mostly owing to the hunting to extinction of its primary prey, the Moa, by the Maori around that time.
Because of "reasons" I am sleeping like crap lately so yes I messed up and mixed up two things
It doesn't help I am only sleeping 3 to 5 hours a day
0
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BroloBroseidonLord of the BroceanRegistered Userregular
Metzger MeisterIt Gets Worsebefore it gets any better.Registered Userregular
edited August 2019
A piece of tanzanite that big is probably worth a few thousand dollars at least, it's a pretty rare mineral!
Edit: well I guess there's actually no way to tell how big it is, my brain just went "BIG SHINY ROCK"
Metzger Meister on
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BroloBroseidonLord of the BroceanRegistered Userregular
TEXT:
Last week, the Washington Post reported that the White House had been briefed on a plan to create an agency called HARPA, a healthcare counterpart to the Pentagon’s research and development arm DARPA. Among other initiatives, this new agency would reportedly collect volunteer data from a suite of smart devices, including Apple Watches, Fitbits, Amazon Echos, and Google Homes in order to identify “neurobehavioral signs” of “someone headed toward a violent explosive act.” The project would then use artificial intelligence to create a “sensor suite” to flag mental changes that make violence more likely.
According to the Post, the HARPA proposal was discussed with senior White House officials as early as June 2017, but has “gained momentum” after the mass shootings in El Paso, Texas, and Dayton, Ohio. The latest version of the plan, reportedly submitted to the Trump administration this month, outlined the biometric project called “SAFE HOME,” an acronym for “Stopping Aberrant Fatal Events by Helping Overcome Mental Extremes.” A source told the newspaper that every time HARPA has been discussed in the White House “even up to the presidential level, it’s been very well-received.”
For the HARPA system every person will be given an ID that is digitally tattooed to their identity. Evangelicals insistent Obama is still the antichrist.
DepressperadoI just wanted to see you laughingin the pizza rainRegistered Userregular
if there was one currently extant animal that I'd raise from a pup and use as my WAR MOUNT
it'd definitely be a fuckin' hippo
or a Liger, I think those guys get big enough I could probably ride it, and I could spend the nights while we're Ranging sleeping against its big furry side.
Posts
From a 1 in 4 chance at survival to (if treated quickly) a 1 in 10 or 1 in 20 chance at death.
In this case, where ebola is a really scary disease that's mostly affecting some of the poorest countries in the world, a cure that's too expensive for WHO and various charitable organizations to roll out on a wide scale might as well not exist. Drug manufacturers know that, and would rather get a whole small pie than a big slice of a pie that doesn't exist.
This is the sort of bleak economic calculus that means you can get a once-in-a-lifetime polio vaccine for 75 cents in Pakistan but you need to pay $25 for your flu vaccine every year in the US.
Life has a price tag, and it's more variable than you might think.
Eat at Arby's.
aaaaaaaaaaaaaaaAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-
ACTUALLY NO, THIS IS FINE. LET US PROCEED AS PER OUR INSTRUCTIONS.
There's also the fact that if an exposed family wins at lousy timing and starts going symptomatic on a bus in Kinshasa - or Atlanta, for that matter - things would get Very Very Bad. Nipping that sort of thing in the bud in a place where The Invisible Hand(tm) allows it to be affordable isn't just the right thing to do in and of itself, it prevents some pretty catastrophic scenarios that are really a when-not-if sort of thing if they'd tried to roll out a less affordable treatment to make the next shareholders' meeting happier.
(That and, if it got out that a pharmaceutical company let an outbreak get out of control because they weren't willing to keep the treatment affordable, there would probably be blood in the streets that wasn't a direct result of the virus.)
3:47
Man I want one too
This will be here until I receive an apology or Weedlordvegeta get any consequences for being a bully
it's a fuggin pokemon
Nintendo Network ID: AzraelRose
DropBox invite link - get 500MB extra free.
Haast's Eagle
It lived up until recently +/- 40k years ago as the Maori have legends about them
I cannot find it right now but there is a leathery fossil that was used as either a fetish or weapon during the ice age from haast's eagle
It probably went extinct around the time of the arrival of Europeans, mostly owing to the hunting to extinction of its primary prey, the Moa, by the Maori around that time.
Just let Thor play through, folks. It's not worth it.
https://www.washingtonpost.com/weather/2019/08/27/lightning-struck-pin-th-hole-north-carolina-golf-course-it-left-quite-mark/
Because of "reasons" I am sleeping like crap lately so yes I messed up and mixed up two things
It doesn't help I am only sleeping 3 to 5 hours a day
which sounds sinister with the capital C, but it's only a little bit sinister
Edit: well I guess there's actually no way to tell how big it is, my brain just went "BIG SHINY ROCK"
TEXT:
According to the Post, the HARPA proposal was discussed with senior White House officials as early as June 2017, but has “gained momentum” after the mass shootings in El Paso, Texas, and Dayton, Ohio. The latest version of the plan, reportedly submitted to the Trump administration this month, outlined the biometric project called “SAFE HOME,” an acronym for “Stopping Aberrant Fatal Events by Helping Overcome Mental Extremes.” A source told the newspaper that every time HARPA has been discussed in the White House “even up to the presidential level, it’s been very well-received.”
...p-PreCrime...?
also angry sex is illegal
http://achewood.com/index.php?date=02042003
that's why I only do it asleep style now
at least, I assume I do it
You do, I've got tapes if you want to check.
Uh, I mean
yeah I assume you do as well
bro
man I hope whoever recorded this came out okay
hippos in rivers ain't nuthin to fuck with
it'd definitely be a fuckin' hippo
or a Liger, I think those guys get big enough I could probably ride it, and I could spend the nights while we're Ranging sleeping against its big furry side.