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[COVID-19] -20, -21, -22, -23...

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Posts

  • archivistkitsunearchivistkitsune Registered User regular
    Calica wrote: »
    Folks with allergies, sinus issues, etc.: Can you generally tell when you have a cold, or no?

    I'd say it really depends. The worse the symptoms of allergies, sinuses and other issues, the harder it is to tell. Worse, not all colds are the same. So you could get a very minor cold and write it off as just the same shit from the usual allergies, sinuses or whatever else would normally be causing such symptoms. Also there is the other issue, where if it's something caused by chronic health that isn't seasonal, that if one has to work, they might not have much time to spare to take time off; especially, if they can't be sure they have a cold or not. As some with a chronic health issue, depending on what all is going on, it's really fucking easy to end up in a situation where you have a fuck ton of appointments for the month and more two or more during the same week.

  • ReynoldsReynolds Gone Fishin'Registered User regular
    It's usually the body ache or chills or other symptoms not related to my nose and head that let me know it's a cold and not just allergies.

    uyvfOQy.png
  • monikermoniker Registered User regular
    Reynolds wrote: »
    It's usually the body ache or chills or other symptoms not related to my nose and head that let me know it's a cold and not just allergies.

    Or a persistent scratchy throat. Like, if that's still there after coffee, it's probably not from the radiators/ pollen

  • SolyspSolysp Previously Kane Red Robe Registered User regular
    Calica wrote: »
    Folks with allergies, sinus issues, etc.: Can you generally tell when you have a cold, or no?

    Sometimes. To be honest bad allergy days are more debilitating to me than a mild to moderate cold. If it's just a head cold I might not notice that it's not the usual crap unless I'm really on the lookout for the slightly different order of symptom appearance.

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  • SolyspSolysp Previously Kane Red Robe Registered User regular
    Sneezing in a mask is deeply unpleasant.

  • kimekime Queen of Blades Registered User regular
    I cannot tell the difference

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  • urahonkyurahonky Cynical Old Man Registered User regular
    I have allergies, asthma, and nasal polyps. I'm almost always having issues with my sinuses and cannot tell the difference between a cold and a sinus problem. I just assume a cold and avoid people.

  • redxredx I(x)=2(x)+1 whole numbersRegistered User regular
    edited March 2022
    Calica wrote: »
    Folks with allergies, sinus issues, etc.: Can you generally tell when you have a cold, or no?

    not really. Like, are allergy counts high? Are other people complaining about it on social media? Am I not running a fever?

    Then it's probably allergies.

    Symptom wise, not really.

    Allergies respond to antihistamines, eventually, most of the time.

    redx on
    They moistly come out at night, moistly.
  • wobblyheadedbobwobblyheadedbob Registered User regular
    Sneezing in a mask is deeply unpleasant.

    Also burping.

  • burboburbo Registered User regular
    Also farting.

    Wait, am i wearing my mask wrong?

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  • TetraNitroCubaneTetraNitroCubane Not Angry... Just VERY Disappointed...Registered User regular

    No wonder BA.2 is causing so much transmissibility trouble
    — ~175,000 nasopharyngeal samples analyzed for viral load
    — BA.2 nearly twice as much as BA.1
    Article Link

    Eric Topol is a professor of molecular medicine at Scripps Research.

  • GimGim a tall glass of water Registered User regular
    I'm tired of Covid Borg-ing like this.

    Is there a Covid Queen we can take out?

  • zepherinzepherin Russian warship, go fuck yourself Registered User regular
    Calica wrote: »
    Folks with allergies, sinus issues, etc.: Can you generally tell when you have a cold, or no?
    Not initially. Generally congestion headache coughing. Is it cold flu or allergies? Unknown.

    If I get alternating sweats and chills, I’m sick, but one upper respiratory and another is hard to determine.

  • urahonkyurahonky Cynical Old Man Registered User regular

    No wonder BA.2 is causing so much transmissibility trouble
    — ~175,000 nasopharyngeal samples analyzed for viral load
    — BA.2 nearly twice as much as BA.1
    Article Link

    Eric Topol is a professor of molecular medicine at Scripps Research.

    This is odd since it's also evading the rapid test results more. You'd think if there were twice as much viral load then it'd be easier to detect using a swab.

  • TetraNitroCubaneTetraNitroCubane Not Angry... Just VERY Disappointed...Registered User regular
    edited March 2022
    urahonky wrote: »

    No wonder BA.2 is causing so much transmissibility trouble
    — ~175,000 nasopharyngeal samples analyzed for viral load
    — BA.2 nearly twice as much as BA.1
    Article Link

    Eric Topol is a professor of molecular medicine at Scripps Research.

    This is odd since it's also evading the rapid test results more. You'd think if there were twice as much viral load then it'd be easier to detect using a swab.

    The rapid tests don't check for viral load. They check to see if your body is generating the antigens against the virus. If your body is not yet generating antigens, the rapid tests will come back negative regardless of infection status.

    TetraNitroCubane on
  • urahonkyurahonky Cynical Old Man Registered User regular
    urahonky wrote: »

    No wonder BA.2 is causing so much transmissibility trouble
    — ~175,000 nasopharyngeal samples analyzed for viral load
    — BA.2 nearly twice as much as BA.1
    Article Link

    Eric Topol is a professor of molecular medicine at Scripps Research.

    This is odd since it's also evading the rapid test results more. You'd think if there were twice as much viral load then it'd be easier to detect using a swab.

    The rapid tests don't check for viral load. They check to see if your body is generating the antigens against the virus. If your body is not yet generating antigens, the rapid tests will come back negative regardless of infection status.

    Interesting! I 100% thought they were checking for viral load.

    Makes sense now that it's called Rapid Antigen Test lmao. Some days I'm literally the dumbest person.

  • GilgaronGilgaron Registered User regular
    Minor quibble, antigens aren't against the virus, they are subparts of the virus. The test has antibodies in it that bind them. So, it is measuring if a detectable number of virus pieces are spewing out of your cells, which may or may not be infectious particles depending on how good a job your immune system is doing roughing them up. The rapid antigen tests are qualitative (postive/negative, designed to change color beyond a threshold). You could do a quantitative antigen test via ELISA on a 96 well plate.

    An antibody test can be performed to see if you've had prior exposure to the virus (qualitative) or to measure your titer (quantitative).

    Real time PCR is usually performed quantitatively (Ct number) on the instrument and then reported qualitative (Ct number > threshold: positive).

    Each technology is telling you something a little bit different than the others if you're looking at quantitative numbers vs the qualitative 'Positive'.

    Aside for further upthread: While sneezing in a mask is unpleasant, sneezing in a PAPR is deeply shameful.

  • Jubal77Jubal77 Registered User regular
    edited March 2022
    https://pubmed.ncbi.nlm.nih.gov/35333945/

    Comparisons of the risk of myopericarditis between COVID-19 patients and individuals receiving COVID-19 vaccines: a population-based study

    Results: This study included 11,441 COVID-19 patients from Hong Kong, four of whom suffered from myopericarditis (rate per million: 326; 95% confidence interval [CI] 127-838). The rate was higher than the pre-COVID-19 background rate in 2019 (rate per million: 5.5, 95% CI 4.1-7.4) with a rate ratio of 55.0 (95% CI 21.4-141). Compared to the background rate, the rate of myopericarditis among vaccinated subjects in Hong Kong was similar (rate per million: 5.5; 95% CI 4.1-7.4) with a rate ratio of 0.93 (95% CI 0.69-1.26). The rates of myocarditis after vaccination in Hong Kong were comparable to those vaccinated in the United States, Israel, and the United Kingdom.

    population study finds vaccines cause of myopericarditis (inflammation of pericardium and myocarditis) to be equal to background noise with a significant sample size. The difference being several orders of magnitude when compared to covid-19 patients.

    Jubal77 on
  • thatassemblyguythatassemblyguy Janitor of Technical Debt .Registered User regular
    FDA approved second booster for 50+ crowd:

    https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-second-booster-dose-two-covid-19-vaccines-older-and
    * A second booster dose of the Pfizer-BioNTech COVID-19 Vaccine or Moderna COVID-19 Vaccine may be administered to individuals 50 years of age and older at least 4 months after receipt of a first booster dose of any authorized or approved COVID-19 vaccine.

    * A second booster dose of the Pfizer-BioNTech COVID-19 Vaccine may be administered to individuals 12 years of age and older with certain kinds of immunocompromise at least 4 months after receipt of a first booster dose of any authorized or approved COVID-19 vaccine. These are people who have undergone solid organ transplantation, or who are living with conditions that are considered to have an equivalent level of immunocompromise.

    * A second booster dose of the Moderna COVID-19 Vaccine may be administered at least 4 months after the first booster dose of any authorized or approved COVID-19 vaccine to individuals 18 years of age and older with the same certain kinds of immunocompromise.

  • Magus`Magus` The fun has been DOUBLED! Registered User regular
    Hopefully those don't go to waste.

  • Gnome-InterruptusGnome-Interruptus Registered User regular
    Jubal77 wrote: »
    https://pubmed.ncbi.nlm.nih.gov/35333945/

    Comparisons of the risk of myopericarditis between COVID-19 patients and individuals receiving COVID-19 vaccines: a population-based study

    Results: This study included 11,441 COVID-19 patients from Hong Kong, four of whom suffered from myopericarditis (rate per million: 326; 95% confidence interval [CI] 127-838). The rate was higher than the pre-COVID-19 background rate in 2019 (rate per million: 5.5, 95% CI 4.1-7.4) with a rate ratio of 55.0 (95% CI 21.4-141). Compared to the background rate, the rate of myopericarditis among vaccinated subjects in Hong Kong was similar (rate per million: 5.5; 95% CI 4.1-7.4) with a rate ratio of 0.93 (95% CI 0.69-1.26). The rates of myocarditis after vaccination in Hong Kong were comparable to those vaccinated in the United States, Israel, and the United Kingdom.

    population study finds vaccines cause of myopericarditis (inflammation of pericardium and myocarditis) to be equal to background noise with a significant sample size. The difference being several orders of magnitude when compared to covid-19 patients.

    Are those unvaccinated Covid patients? Or just anyone who had managed to catch Covid at all?

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  • kimekime Queen of Blades Registered User regular
    edited March 2022
    Jubal77 wrote: »
    https://pubmed.ncbi.nlm.nih.gov/35333945/

    Comparisons of the risk of myopericarditis between COVID-19 patients and individuals receiving COVID-19 vaccines: a population-based study

    Results: This study included 11,441 COVID-19 patients from Hong Kong, four of whom suffered from myopericarditis (rate per million: 326; 95% confidence interval [CI] 127-838). The rate was higher than the pre-COVID-19 background rate in 2019 (rate per million: 5.5, 95% CI 4.1-7.4) with a rate ratio of 55.0 (95% CI 21.4-141). Compared to the background rate, the rate of myopericarditis among vaccinated subjects in Hong Kong was similar (rate per million: 5.5; 95% CI 4.1-7.4) with a rate ratio of 0.93 (95% CI 0.69-1.26). The rates of myocarditis after vaccination in Hong Kong were comparable to those vaccinated in the United States, Israel, and the United Kingdom.

    population study finds vaccines cause of myopericarditis (inflammation of pericardium and myocarditis) to be equal to background noise with a significant sample size. The difference being several orders of magnitude when compared to covid-19 patients.

    Are those unvaccinated Covid patients? Or just anyone who had managed to catch Covid at all?

    Skimming through the full text (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951670/), it looks like the latter:
    Patients who tested positive for COVID-19 by real-time polymerase chain reaction (RT-PCR) at any of the Hong Kong public hospitals or outpatient clinics between 1st January 2020 and 30th June 2021 were included.

    But recognize that the majority of the people getting tested for Covid at a hospital are gonna be unvaccinated folks. But not everyone.

    Edit: That said, they go further in to describe that the testing practices in Hong Kong are less likely to miss folks due to a lot of contact tracing and such. So, you would expect that this is actually "most people who got Covid in Hong Kong" according to the study.

    So, their conclusion is basically "maybe the vaccines cause myopericarditis, our study isn't saying conclusively that they don't. But Covid causes it a lot more. And Covid is running rampant and so getting the vaccine is the best way to reduce the risk of myopericarditis."

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  • Jubal77Jubal77 Registered User regular
    edited March 2022
    kime wrote: »
    Jubal77 wrote: »
    https://pubmed.ncbi.nlm.nih.gov/35333945/

    Comparisons of the risk of myopericarditis between COVID-19 patients and individuals receiving COVID-19 vaccines: a population-based study

    Results: This study included 11,441 COVID-19 patients from Hong Kong, four of whom suffered from myopericarditis (rate per million: 326; 95% confidence interval [CI] 127-838). The rate was higher than the pre-COVID-19 background rate in 2019 (rate per million: 5.5, 95% CI 4.1-7.4) with a rate ratio of 55.0 (95% CI 21.4-141). Compared to the background rate, the rate of myopericarditis among vaccinated subjects in Hong Kong was similar (rate per million: 5.5; 95% CI 4.1-7.4) with a rate ratio of 0.93 (95% CI 0.69-1.26). The rates of myocarditis after vaccination in Hong Kong were comparable to those vaccinated in the United States, Israel, and the United Kingdom.

    population study finds vaccines cause of myopericarditis (inflammation of pericardium and myocarditis) to be equal to background noise with a significant sample size. The difference being several orders of magnitude when compared to covid-19 patients.

    Are those unvaccinated Covid patients? Or just anyone who had managed to catch Covid at all?

    Skimming through the full text (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8951670/), it looks like the latter:
    Patients who tested positive for COVID-19 by real-time polymerase chain reaction (RT-PCR) at any of the Hong Kong public hospitals or outpatient clinics between 1st January 2020 and 30th June 2021 were included.

    But recognize that the majority of the people getting tested for Covid at a hospital are gonna be unvaccinated folks. But not everyone.

    Hong Kong didnt start administering doses until end of Feb '21. By June 21 the representative population of one dose only accounted for ~20%. So the representation would heavily lean towards unvaccinated in the study.

    Jubal77 on
  • Undead ScottsmanUndead Scottsman Cybertronian Paranormal Eliminator Registered User regular
    There was an outbreak in the Alaskan Legislature, and the House required all members to wear masks and some Republicans refused, so now floor session has been canceled for two consequtive days now.

    I mean it's not like Alaska has the highest rate of covid in the US per capita right now, so why mask up?

  • urahonkyurahonky Cynical Old Man Registered User regular
    There was an outbreak in the Alaskan Legislature, and the House required all members to wear masks and some Republicans refused, so now floor session has been canceled for two consequtive days now.

    I mean it's not like Alaska has the highest rate of covid in the US per capita right now, so why mask up?

    Shit sounds like they got some free paid time off.

  • Jubal77Jubal77 Registered User regular
    "Well what about clinical trials"

    [...] A double-blind, randomized, placebo-controlled, adaptive platform trial involving symptomatic SARS-CoV-2–positive adults [...,] Treatment with ivermectin did not result in a lower incidence of medical admission to a hospital due to progression of Covid-19 or of prolonged emergency department observation among outpatients with an early diagnosis of Covid-19.

    https://www.nejm.org/doi/full/10.1056/NEJMoa2115869

  • TetraNitroCubaneTetraNitroCubane Not Angry... Just VERY Disappointed...Registered User regular
    edited March 2022
    Your Local Epidemiologist has a new article up discussing the power of ventilation and filtration.
    Research has shown that ventilation and filtration can do a lot for SARS-CoV-2:
    • A study last summer found that open windows in classrooms can have up to a 14.1 fold reduction in COVID19 transmission. This was highly dependent on the time of year (summer, spring, winter), number of windows, and how frequently those windows are open.
    • A Johns Hopkins study found that HEPA filters were responsible for a 65% drop in COVID-19 transmission.
    • Another study found that one HEPA filter is as effective as two windows partly open all day during the winter (2.5-fold decrease in transmission). Two HEPA filters are even more effective (4-fold decrease in transmission).
    • And, most recently, a data analysis in Italy found ventilation in schools can reduce the risk of infection up to 82%.

    It's a good discussion, and something we all need to think about moving forward desperately. It's a huge part of public health that's gone neglected for too long.

    TetraNitroCubane on
  • monikermoniker Registered User regular
    Your Local Epidemiologist has a new article up discussing the power of ventilation and filtration.
    Research has shown that ventilation and filtration can do a lot for SARS-CoV-2:
    • A study last summer found that open windows in classrooms can have up to a 14.1 fold reduction in COVID19 transmission. This was highly dependent on the time of year (summer, spring, winter), number of windows, and how frequently those windows are open.
    • A Johns Hopkins study found that HEPA filters were responsible for a 65% drop in COVID-19 transmission.
    • Another study found that one HEPA filter is as effective as two windows partly open all day during the winter (2.5-fold decrease in transmission). Two HEPA filters are even more effective (4-fold decrease in transmission).
    • And, most recently, a data analysis in Italy found ventilation in schools can reduce the risk of infection up to 82%.

    It's a good discussion, and something we all need to think about moving forward desperately. It's a huge part of public health that's gone neglected for too long.

    It's definitely going to be a part of new ASHRAE guidelines (though that's slow to take effect, but it is also like a tsunami that never ends) and even better, air handlers can get retrofitted for HEPA filters fairly easily and also, it looks like there are some non-cancerous UV lights that might also work well and probably wouldn't need as expensive shielding.

    https://www.nature.com/articles/s41598-022-08462-z

    A lot of these sorts of things already exist to some extent in hospitals and labs, it would just be a matter of bringing cost down to implement/ require them in other settings without making new construction even more difficult.

  • webguy20webguy20 I spend too much time on the Internet Registered User regular
    moniker wrote: »
    Your Local Epidemiologist has a new article up discussing the power of ventilation and filtration.
    Research has shown that ventilation and filtration can do a lot for SARS-CoV-2:
    • A study last summer found that open windows in classrooms can have up to a 14.1 fold reduction in COVID19 transmission. This was highly dependent on the time of year (summer, spring, winter), number of windows, and how frequently those windows are open.
    • A Johns Hopkins study found that HEPA filters were responsible for a 65% drop in COVID-19 transmission.
    • Another study found that one HEPA filter is as effective as two windows partly open all day during the winter (2.5-fold decrease in transmission). Two HEPA filters are even more effective (4-fold decrease in transmission).
    • And, most recently, a data analysis in Italy found ventilation in schools can reduce the risk of infection up to 82%.

    It's a good discussion, and something we all need to think about moving forward desperately. It's a huge part of public health that's gone neglected for too long.

    It's definitely going to be a part of new ASHRAE guidelines (though that's slow to take effect, but it is also like a tsunami that never ends) and even better, air handlers can get retrofitted for HEPA filters fairly easily and also, it looks like there are some non-cancerous UV lights that might also work well and probably wouldn't need as expensive shielding.

    https://www.nature.com/articles/s41598-022-08462-z

    A lot of these sorts of things already exist to some extent in hospitals and labs, it would just be a matter of bringing cost down to implement/ require them in other settings without making new construction even more difficult.

    Large scale adoption would probably help drive cost through volume. One place we cant neglect is schools, which will be hard because so many already are neglected.

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  • Captain InertiaCaptain Inertia Central OhioRegistered User regular
    Schools? You mean those dilapidated day cares for old kids?

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  • monikermoniker Registered User regular
    webguy20 wrote: »
    moniker wrote: »
    Your Local Epidemiologist has a new article up discussing the power of ventilation and filtration.
    Research has shown that ventilation and filtration can do a lot for SARS-CoV-2:
    • A study last summer found that open windows in classrooms can have up to a 14.1 fold reduction in COVID19 transmission. This was highly dependent on the time of year (summer, spring, winter), number of windows, and how frequently those windows are open.
    • A Johns Hopkins study found that HEPA filters were responsible for a 65% drop in COVID-19 transmission.
    • Another study found that one HEPA filter is as effective as two windows partly open all day during the winter (2.5-fold decrease in transmission). Two HEPA filters are even more effective (4-fold decrease in transmission).
    • And, most recently, a data analysis in Italy found ventilation in schools can reduce the risk of infection up to 82%.

    It's a good discussion, and something we all need to think about moving forward desperately. It's a huge part of public health that's gone neglected for too long.

    It's definitely going to be a part of new ASHRAE guidelines (though that's slow to take effect, but it is also like a tsunami that never ends) and even better, air handlers can get retrofitted for HEPA filters fairly easily and also, it looks like there are some non-cancerous UV lights that might also work well and probably wouldn't need as expensive shielding.

    https://www.nature.com/articles/s41598-022-08462-z

    A lot of these sorts of things already exist to some extent in hospitals and labs, it would just be a matter of bringing cost down to implement/ require them in other settings without making new construction even more difficult.

    Large scale adoption would probably help drive cost through volume. One place we cant neglect is schools, which will be hard because so many already are neglected.

    It would, but still will constitute a bump in costs from the current standard that doesn't rely it and that will be 100% pass through. Assuming it doesn't even just get VE'd down to technically compliant.

  • Librarian's ghostLibrarian's ghost Librarian, Ghostbuster, and TimSpork Registered User regular
    Imagine being in a school that had opening windows.

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  • evilmrhenryevilmrhenry Registered User regular
    Imagine being in a school that had opening windows.

    Not as bit of an issue as you might think. If there's a HVAC system, there's almost certainly an inline HEPA grade filter you can add. If there isn't, you can stick stand-alone HEPA filters in rooms instead. Neither is perfect, but both will drastically cut down on virus aerosols. And that's ignoring UV lights; a UV light in a box and a fan can have similar effects, for potentially less money.

  • PreacherPreacher Registered User regular


    LA Times reporter

    Study: When white Americans heard about COVID hitting people of color harder, a lot of them mentally peaced out. This is ugly. https://sciencedirect.com/science/article/abs/pii/S027795362200257X

    Everyone probably already knew this, but a study literally found it. But remember racism is not an issue in america.

    I would like some money because these are artisanal nuggets of wisdom philistine.

    pleasepaypreacher.net
  • GvzbgulGvzbgul Registered User regular
    Unsurprising, education about racial disparity can often have unintended effects. Eg, one study found that teaching about white privilege didn't increase sympthy towards a hypothetical poor black person but it did decrease sympathy towards a hypothetical poor white person. People seem predisposed to take the worst lesson from a learning opportunity.

  • PreacherPreacher Registered User regular
    What's kind of funny in an ironic way. When those same people would ignore the science white people died as a higher % of the population than minorities. Their racism literally ended up killing them.

    I would like some money because these are artisanal nuggets of wisdom philistine.

    pleasepaypreacher.net
  • CelestialBadgerCelestialBadger Registered User regular
    Americans are programmed to dismiss all social problems the moment they hear it primarily affects black people. I'm pretty sure Covid hit black people harder initially because they tend to live in densely populated cities. This did not mean that it was some sort of "black people mainly disease" like sickle cell. Subsequent waves hit the countryside, suburbs and white people hard.

This discussion has been closed.