Secret Six #36, one of the best final issues in a good long while, similar to Thunderbolts #75.
So the six find a warehouse for their base of operations, but there's a homeless family inside. On top of it the Penguin had a tracker installed in him and Huntress calls down every hero imaginable, so the six are cornered. But along the way we have nice interludes with all the group, like so:
And then Huntress tries to replace the family held hostage:
and ultimately the group goes out with a bang, taking on the whole group of heroes (super-family included) by taking Venom. They lose, of course, but then again the Secret Six never win.
Thunderbolts #161, twists and turns abound!
A missle is heading for Chicago, only Moonstone can save it!
but the missile was heading for the lake all along because it contained shrunken down crab people who turn full size when exposed to water, like those sponge toys! On top of that Satanna moves the entire Raft to Chicago to help the A-team, wowza!