so right what I want to get across in this whitepaper is a few things, among which: yes, biotech is futuristic and AI is futuristic. You do realize that like...that doesn't mean AI solves biotech, right?
AI does specific things. Any given biotech problem involves some specific steps. You gotta ask some actual fucking working scientists what those steps are, and then figure out if AI will in any way make them faster or better (or enable you to circumvent the steps or paradigm shift but let's be real if you have to ask the scientists what the process is you do not have the knowledge for a paradigm shifting ai concept) and you have to be ready for the answer to be no. Like. I just read some garbage Time article someone posted at work being like, the age of biotech AI is now! Biotech uses CRISPR, so AI will solve that! And it's like. What the fuck do you think CRISPR is? (it is a biochemical process where you put some proteins and some nucleotides in an animal. You design what nucleotides in order to decide what specific part of the genome you will edit. You are editing the genome because you are looking to create a mouse with a specific genetic condition. You are making a mouse with a specific genetic condition for any number of reasons but you have chosen which genetic condition in accordance with your specific experimental goals (e.g., design a fat mouse so you can test diabetes drugs)) Ok now that you've taken the time to learn in the just vaguest terms what CRISPR is, why do you think AI would help do this in any way? like what part of the process would AI do...? Actually, maybe you better go ask someone who understands AI what AI can do, cause otherwise you won't be able to answer that either.
What is your actual goal? Your goal can't just be 'introduce AI to my org'. Like what are you actually fucking trying to do? You want to cure cancer? no you do not want to cure cancer, that is not a real thing. Maybe what you mean is you are looking to find a small molecule that inhibits a protein involved in a common cancer pathway? That sounds more like a real thing. How do scientists go about that? Well, one thing that they might do is virtually throw a bunch of small molecules against 3D structures of proteins, and see if any of them nestle in nicely. But, if you don't have a 3D structure of a protein you care about, you can use alphafold to generate a plausible one, most of the time. Hey that's AI, good job! And hey honestly, if you want to identify some promising proteins in the just absolutely horribly cluttered bazillion cancer papers out there, could to worse than to ask chatGPT to give you a list. Hey you used AI again, good job! Ok cool so now you did this docking simulation and used AI twice, do you have a drug? Lol no now you have to test it in cells and in mice and in people. How are we gonna use AI to do that? ummmmmm I mean. You could use a pipetting robot...
--anyway
i have feelings
about this
hopefully I will write this all out and get it published in our stupid consulting magazine, we will see. I have a whole like categories of what AI does and where in the process and how you can break your process down and see if any of the categories make sense. maybe I'll make some ~process graphics~ and such
Speaking of The Mask (it happened on the last page, I swear!) I recently picked up a cheap copy and, finding that it pleasantly holds up, listened to the commentary with director Chuck Russell.
First off, it's adorable when he suggests viewers slow down a scene on their "LaserDisc deck", and a little heartbreaking how excited he sounds about the fact that he'd recently (at the time of recording, presumably in the late 90s) heard that New Line was looking to get everyone back together for a sequel.
But he also describes a fairly fun series of events. It seems that Spielberg was looking into doing a Plastic Man movie, and Russel had been brought in for a meeting on it. He suggested that they push in a more comedic direction, as well as looking into this guy on In Living Color named Jim Carrey for the lead. Spielberg passed on that. And then New Line had bought the rights to grimy Dark Horse comic The Mask, and brought him in, wanting a horror movie. Russel suggested that they push in a more comedic direction, as well as looking into this guy on In Living Color named Jim Carrey for the lead. New Line passed on that... for awhile. But after repeated horror-focussed The Mask scripts weren't working, they circled back around to Russel, let him cast TV's Jim Carrey as the lead, and go full Tex Avery with the script.
(He also has a lot of insight into working with the dog, and for as good as Milo's performer is in the movie, I think a lot of credit goes to Russel. Like when he's taking the keys, it was Russel who moved the trainer to be off camera behind the sleeping police officer, so that it looks like Milo's worried about him waking up. Over and over, it's mentioned that "tricks" are boring if that's all they are, and animals are most interesting if you can finesse them into seeming like they're acting.)
Oh, and he was repeatedly pushed (while filming) to cut the Cuban Pete scene, and raced to have it finished for early test screenings, where audiences generally ranked it as their favourite part of the movie.
So I haven't had a chance to see how many other examples there are, but the campus protests in Europe are succeeding in forcing policy changes. Trinity University in Dublin and Barcelona University have both agreed to cut ties with Israeli institutions and divest.
There is a room on Microsoft campus in the basement of one of the buildings that is soundproof. Huge thick steel and who knows what walls. And the whole thing is floating on a pool of mineral oil. So you have to go through this airlock like door.
It is so quiet that it is actually disturbing to be in there. They do sound editing for stuff like the windows sound effects there.
That reminds me that Clueless came on the TV and me and my wife watched it one night and that movie still holds up and motherfucking Paul Rudd is a goddamn immortal and someone should check his house for his sword.
This is real "He was just really tired of that turbulent priest, he wasn't the one who actually got rid of him" territory to be trying to argue that Biden's rhetoric about the pro-Palestinian protestors, where he has been denouncing them and saying they are crossing the lines of acceptable protest, is something that can't be considered a contributing factor to the increased demonization of protestors, nor a sign of encouragement/approval to those who decide to deploy law enforcement to break up these groups.
Who do you think Biden is calling out when he says that there is no place on any campus for antisemitism, threats of violence and destroying property? Who is he calling violent and lawless then?
Because he is 100% calling someone out for being/doing all those things, @iTunesIsEvil , please explain to me who specifically is Biden refering to in that quote.