Ever wonder why the old villain tutorial has you being broken out of The Zig? Why can't you break out from the inside? Why is everyone that escapes so low on the power totem pole?
So Pandora's Box was being used as a Power Dampening Field under The Zig the entire time it was open. It was specifically put there for this purpose, though I'm not sure if the placers of The Box knew WHY it was doing what it does, just that it was a box that happened to dampen powers. You find this out just in time to find out that it's been stolen and there's now nothing preventing these amazingly super powered criminals from just busting a hole through the Zig Wall.
Which, as anyone who read the preview for i24 knows, is exactly what happens.