I'm about to get back into the IT business after 6 years away. I'm sure things have changed somewhat. Most of my work in the previous decade was cleaning up the shit that users somehow got onto their systems, so I'm interested to know what tools are used these days to clean them up. Previously I used Ad-Aware, Spybot, and HIjackThis for most of my work (this was 2002-2006). Any tips on what to use these days?