Its just a "the more you know, the better" scenario. The more scientists know about how these little buggers work, the faster they can combat disease and other nasty things. Knowledge is power, yo.
I'm glad everyone's enjoying themselves and I want to thank everyone for keeping console politics out of it. Cheers to all our PC/Mac/Linux folken - and thank you to our PS3 users. Everyone is welcome for our grand opening of ps3arcadians.com shortly.
As soon as I can get the bloody MySQL stuff figured out.
Need any volunteers to help? My design sense sucks, but I do write database driven web apps for a living. :rotate:
I think I could use a hand. I'm trying to use phpMyAdmin to configure the database, but I'm not sure I'm doing it right. I might be knocking on your PM door shortly Thanks!
Alright lads, I'm going to do a draw for a random prize. Give me about 20 minutes to get the names printed and the bits cut up and we'll have another prize given away!
Folks, if you're not on board, jump in - team 54717 - "Folding Arcadians". Punch and pie, prizes and goood times!
Alright lads, I'm going to do a draw for a random prize. Give me about 20 minutes to get the names printed and the bits cut up and we'll have another prize given away!
Folks, if you're not on board, jump in - team 54717 - "Folding Arcadians". Punch and pie, prizes and goood times!
Bah, my first WU won't finish for another couple of hours hehe. Oh well
mntorankusuI'm not sure how to use this thing....Registered Userregular
edited March 2007
I have a sad story to tell. I left the F@H program open on my laptop last night, and it was getting through it pretty quickly, so I expected one unit to be done sometime today. But this morning, I woke up to find that the plug had been pulled out of the wall somehow, and my laptop was off, its battery dead.
I opened up the program again, and it said:
Error opening or reading from a file.
Deleting current work unit & continuing...
This might be a stupid question but - I'm running it on my PC and have set it to use 100% of my processor but it seems to only be using 50% consistently when I check in task manager. Is this because of the dual-core? Is the only way to utilize it 100% to install it twice? Using the 2.93GHz Core 2 Duo.
This might be a stupid question but - I'm running it on my PC and have set it to use 100% of my processor but it seems to only be using 50% consistently when I check in task manager. Is this because of the dual-core? Is the only way to utilize it 100% to install it twice? Using the 2.93GHz Core 2 Duo.
I'm fairly sure thats correct, you need to be running it twice to use both cores.
This might be a stupid question but - I'm running it on my PC and have set it to use 100% of my processor but it seems to only be using 50% consistently when I check in task manager. Is this because of the dual-core? Is the only way to utilize it 100% to install it twice? Using the 2.93GHz Core 2 Duo.
I'm fairly sure thats correct, you need to be running it twice to use both cores.
I've been wondering this too, as my next computer will likely be dual core and run Linux. I just read on the F@H site that there's a (beta) client for OS X (Intel version) and Linux that lets it use multiple cores pretty easily. You can get it here. It appears that this might also work for Windows, but it looks complicated, and all versions still have some bugs. Could be worth testing out though, for those of you with dual core machines.
ALSO please keep in mind that as awesome as the PS3 and GPU clients are, they are NOT general-purpose folders. They can only handle a subset of the projects that CPUs can (although they do it hella-fast). The CPU client may be lagging behind in overall TFlops, but it's still VERY necessary for the cause.
I'm running the SMP beta on my intel iMac and my Macbook - it chews up 100% of available both processors so I only run it while I'm not using the machines, but it's easy to turn on and off through the System Preferences. I think I'll write an automator action to start it and pop me into the login screen when I'm walking away.
This might be a stupid question but - I'm running it on my PC and have set it to use 100% of my processor but it seems to only be using 50% consistently when I check in task manager. Is this because of the dual-core? Is the only way to utilize it 100% to install it twice? Using the 2.93GHz Core 2 Duo.
I'm fairly sure thats correct, you need to be running it twice to use both cores.
I've been wondering this too, as my next computer will likely be dual core and run Linux. I just read on the F@H site that there's a (beta) client for OS X (Intel version) and Linux that lets it use multiple cores pretty easily. You can get it here. It appears that this might also work for Windows, but it looks complicated, and all versions still have some bugs. Could be worth testing out though, for those of you with dual core machines.
Yeah, I should have specified, I think you need to run it twice to use both cores in windows.
Running right now on my PC (no PS3 to run it on) and the estimated time sees to be rediculous (100+ days). But it's dropping by hours everytime it updates so I'm not really sure what to make of it lol
Basically the group in question are looking at how the individual amino acids of a protein interact that give the molecule it's final form. So to put this into English, imagine having several differently coloured pieces of paper (some red, blue, white etc) and putting them together into such a way that you form a 3d structure like a cube, or perhaps a sphere or whatever. The pieces of paper and the positions they are in represent different amino acids and the final conformation (the cube etc) is the final 'folded' protein. What scientists have been trying to figure out for a while now is how the amino acid sequence determines how the final protein folds. We know that some of these amino acids have different kinds of chemical behaviour in a cell, with some of them being hydrophobic (IE: They don't like to be next to water molecules) and some of them hydrophillic (IE: They prefer to be surrounded by water molecules).
The problem is that even though a lot of people have done quite a bit of work on simulating how proteins fold, it hasn't been a very successful endeavor. Programming a simulation that accurately predicts how a protein ends up folding from the linear string of amino acids into the final conformation has numerous problems, inlcuding that other proteins are often involved and that the base amino acid sequence doesn't always fold how you'd predict just looking at it. The other problem is that proteins (in a cell) fold into their final conformation in an incredibly short period of time (in the range of nano-seconds, IE: millionths of a second), but for a computer to simulate this takes a lot more effort and time. IIRC, it takes several days for a computer to simulate the folding of a simple protein and that's not really a very time efficient process. Add to this the fact you will have to run these simulations many times to get the most accurate picture you can and you're starting to spend years trying to figure out how a single protein folds.
Hence, what scientists are trying to do with Folding@home is to basically increase the amount of CPU power available to decrease the time it takes for each simulation to run. The other advantage is they can presumably look at a wider array of proteins as well, giving them a much more accurate overall impression than just running a single molecule.
This will lead to potentially new treatments for diseases like Alzheimer's because many diseases are caused by proteins folding in a way that isn't correct (and we do not understand the exact mechanism behind this). As an example, Alzheimer's is caused when a protein misfolds itself into a conformation where it forms a structure that allows it to 'stick' to other similarly misfolded proteins. The misfolded proteins then start to build up into an ever expanding mass, forming 'plaques' in neuronal cells, which induce cell senescence and subsequent deactivation (or death). If we can understand and predict why the proteins fold abnormally, we might be able to interfere with the folding process to stop it or force the proteins to fold normally again, which could considerably help a disease like Alzheimer's.
Alright, I'm in - same name: Jensen. (I'm boring, it's also my real name :P )
Just so I'm clear, it's cool that I put the 54717 team number in even though I'm not using a ps3? This isn't a ps3 exclusive group is it, cuz I know there's a team Penny Arcade too.
up to two computers now.. installed it on my dad's computer as a service, but when I first ran it as a console it was working on the same protein as this one.
Just need to get my regular computer back up and running.. all 3 combined = almost 3GHz.
edit: apparently this computer will finish it's job on April 2nd. Jeez.
i was running the console and graphic versions simultaneously on my dual core..and i just found out the hard way apparently the console version..or my install of it anyway doesnt resume where it left off after a restart like the graphic version...it was like.. 95% done too..
Awesome - welcome to the team everybody! This is most certainly not a PS3 exclusive group - although the website is found at (wait for it)
PS3Arcadians.com
and the prizes and gifts are brought to you by the goodwill of a PlayStation 3 owner.
PlayStation 3 - A kinder, gentler console experience™
Hey, cool, I just dinged and got +2 to shilling!
Edit: Seriously though, one of the reasons I'm doing this is because I would like the folks here in G&T to see that most folks who own PS3s aren't frothing troglodytes screaming "This is Living" from the tops of buildings while urinating on flaming 360s. We're a pretty chill bunch (well, most of us) - and I'd rather that everyone get along and discuss the finer points of Games and Tech rather than lengthy flamewars that don't really do much for any of us. Alrighty. I'll go put my soap box away now.
PS3 is currently generating 2.5x the amount of processing power the rest of clients are put together.
Eeesh.
EDIT: I'll get my PC on this soon.
Also, about a 360 client, I understand that the reason the PS3 is good is because of the Cell. However, if you look around you'll notice there's an ATI GPU client, which generates about 60x as much power as a standard PC CPU. There's hope for MS and cancer curing yet if MS pulls their thumb out of their ass!
i was running the console and graphic versions simultaneously on my dual core..and i just found out the hard way apparently the console version..or my install of it anyway doesnt resume where it left off after a restart like the graphic version...it was like.. 95% done too..
if you are running multiple versions (dual core OR GPU/CPU processing) make sure you install/put the executable in different places. The installs will mess each other up otherwise, resulting in bad data/imcomplete results.
Posts
I think I could use a hand. I'm trying to use phpMyAdmin to configure the database, but I'm not sure I'm doing it right. I might be knocking on your PM door shortly Thanks!
Alright lads, I'm going to do a draw for a random prize. Give me about 20 minutes to get the names printed and the bits cut up and we'll have another prize given away!
Folks, if you're not on board, jump in - team 54717 - "Folding Arcadians". Punch and pie, prizes and goood times!
Twitter
This message brought to you by PS3Arcadians :P
Bah, my first WU won't finish for another couple of hours hehe. Oh well
I am a freaking nerd.
I opened up the program again, and it said:
Error opening or reading from a file.
Deleting current work unit & continuing...
A whole day of progress lost! Mankind is doomed!
I need to get more prizes!
Edit: mntorankusu - NOOOOOOOOOOOOOOOO! (someone want to post that Vader image?)
I'm fairly sure thats correct, you need to be running it twice to use both cores.
I am a freaking nerd.
I've been wondering this too, as my next computer will likely be dual core and run Linux. I just read on the F@H site that there's a (beta) client for OS X (Intel version) and Linux that lets it use multiple cores pretty easily. You can get it here. It appears that this might also work for Windows, but it looks complicated, and all versions still have some bugs. Could be worth testing out though, for those of you with dual core machines.
I'd like to encourage you PS3 guys to also run a copy on your computer:
Wait for it....
CHARPUNK!
Congrats char. I've got a list of prizes for you to choose from, so please PM me!
Yeah, I should have specified, I think you need to run it twice to use both cores in windows.
I am a freaking nerd.
Good to hear about ps3arcadians too, superb job!
Count me in. I'm in the team as Shihku7. :-D
We're about to break into the top 10,000 teams - after starting at 55,000 a few days ago. Well done lads!
I am a freaking nerd.
Basically the group in question are looking at how the individual amino acids of a protein interact that give the molecule it's final form. So to put this into English, imagine having several differently coloured pieces of paper (some red, blue, white etc) and putting them together into such a way that you form a 3d structure like a cube, or perhaps a sphere or whatever. The pieces of paper and the positions they are in represent different amino acids and the final conformation (the cube etc) is the final 'folded' protein. What scientists have been trying to figure out for a while now is how the amino acid sequence determines how the final protein folds. We know that some of these amino acids have different kinds of chemical behaviour in a cell, with some of them being hydrophobic (IE: They don't like to be next to water molecules) and some of them hydrophillic (IE: They prefer to be surrounded by water molecules).
The problem is that even though a lot of people have done quite a bit of work on simulating how proteins fold, it hasn't been a very successful endeavor. Programming a simulation that accurately predicts how a protein ends up folding from the linear string of amino acids into the final conformation has numerous problems, inlcuding that other proteins are often involved and that the base amino acid sequence doesn't always fold how you'd predict just looking at it. The other problem is that proteins (in a cell) fold into their final conformation in an incredibly short period of time (in the range of nano-seconds, IE: millionths of a second), but for a computer to simulate this takes a lot more effort and time. IIRC, it takes several days for a computer to simulate the folding of a simple protein and that's not really a very time efficient process. Add to this the fact you will have to run these simulations many times to get the most accurate picture you can and you're starting to spend years trying to figure out how a single protein folds.
Hence, what scientists are trying to do with Folding@home is to basically increase the amount of CPU power available to decrease the time it takes for each simulation to run. The other advantage is they can presumably look at a wider array of proteins as well, giving them a much more accurate overall impression than just running a single molecule.
This will lead to potentially new treatments for diseases like Alzheimer's because many diseases are caused by proteins folding in a way that isn't correct (and we do not understand the exact mechanism behind this). As an example, Alzheimer's is caused when a protein misfolds itself into a conformation where it forms a structure that allows it to 'stick' to other similarly misfolded proteins. The misfolded proteins then start to build up into an ever expanding mass, forming 'plaques' in neuronal cells, which induce cell senescence and subsequent deactivation (or death). If we can understand and predict why the proteins fold abnormally, we might be able to interfere with the folding process to stop it or force the proteins to fold normally again, which could considerably help a disease like Alzheimer's.
Methinks I'll add a link to that to our first post Thanks Aegeri!
Just so I'm clear, it's cool that I put the 54717 team number in even though I'm not using a ps3? This isn't a ps3 exclusive group is it, cuz I know there's a team Penny Arcade too.
Disclaimer: Actual Google banner ad captured at www.serebii.net
Just need to get my regular computer back up and running.. all 3 combined = almost 3GHz.
edit: apparently this computer will finish it's job on April 2nd. Jeez.
MKDS: 1890-3814-0891
MPH: 1031-4679-1259
PS3Arcadians.com
and the prizes and gifts are brought to you by the goodwill of a PlayStation 3 owner.
PlayStation 3 - A kinder, gentler console experience™
Hey, cool, I just dinged and got +2 to shilling!
Edit: Seriously though, one of the reasons I'm doing this is because I would like the folks here in G&T to see that most folks who own PS3s aren't frothing troglodytes screaming "This is Living" from the tops of buildings while urinating on flaming 360s. We're a pretty chill bunch (well, most of us) - and I'd rather that everyone get along and discuss the finer points of Games and Tech rather than lengthy flamewars that don't really do much for any of us. Alrighty. I'll go put my soap box away now.
Eeesh.
EDIT: I'll get my PC on this soon.
Also, about a 360 client, I understand that the reason the PS3 is good is because of the Cell. However, if you look around you'll notice there's an ATI GPU client, which generates about 60x as much power as a standard PC CPU. There's hope for MS and cancer curing yet if MS pulls their thumb out of their ass!
if you are running multiple versions (dual core OR GPU/CPU processing) make sure you install/put the executable in different places. The installs will mess each other up otherwise, resulting in bad data/imcomplete results.
I am a freaking nerd.
I dont think so.
Yay, finally updated and credited for me.
I am a freaking nerd.
Woo.
Steam