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Unless it's being installed by a cat or something else that can accumulate excess amounts of static electricty, or by a gorilla or something else that'll probably wreck your case, swapping out an 8800GTS for an 8800GTS is unlikely to cause any harm.
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If all the other components in his system are working fine until this card is put in you shouldn't have to worry about a short or anything.
Do you have a different card you can try in his board before you put that card in your system? He might have a bad/dead slot.