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Akathisia- a reaction to abilify

KarpmanKarpman Registered User regular
edited March 2008 in Help / Advice Forum
Please, if youi have had this, tell me waht med worked for you to get rid of it. I can't stop moving feeling. I wish I were dead. I am talking to my docs and family. I don't really wish I waere dead, but this is torture. Please, someone help me.

Karpman on

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  • FeralFeral MEMETICHARIZARD interior crocodile alligator ⇔ ǝɹʇɐǝɥʇ ǝᴉʌoɯ ʇǝloɹʌǝɥɔ ɐ ǝʌᴉɹp ᴉRegistered User regular
    edited March 2008
    Is your akathisia induced by other drugs or is it caused by something else?

    There are a lot of drugs that treat it, and the precise one that will work best for you depends a lot on what caused your akathisia and a little bit on random chance. If you're talking to doctors, they should be able to suggest several different kinds of meds to try. you just need to keep plugging away at it until you find something that works.

    Feral on
    every person who doesn't like an acquired taste always seems to think everyone who likes it is faking it. it should be an official fallacy.

    the "no true scotch man" fallacy.
  • RaneadosRaneados police apologist you shouldn't have been there, obviouslyRegistered User regular
    edited March 2008
    Akathisia

    from Wikipedia

    Causes

    Akathisia is most often seen as a side effect of antipsychotic medications, but has other causes as well:

    * Non-sedating antipsychotics[7] such as haloperidol (Haldol), droperidol, pimozide, trifluoperazine, amisulpride, risperidone, and aripiprazole (Abilify). Less common in sedating antipsychotics such as zuclopenthixol (Cisordinol®) or chlorpromazine where anticholinergic and antihistaminergic effects counteract akathisia to a degree.
    * SSRIs, such as fluoxetine (Prozac).[8] It has also been documented with the use of paroxetine (Paxil).[5] Akathisia has been studied as the mechanism by which SSRI-induced suicidality occurs.[8]
    * Other antidepressants, such as the tricyclics and trazodone (Desyrel).
    * Certain anti-emetic drugs, particularly the dopamine blockers, such as metoclopramide (Reglan) and prochlorperazine (Compazine).
    * Certain recreational drugs, such as GHB, methamphetamine and MDMA when administered in excessive doses.

    The 2006 UK study by Healy, Herxheimer, and Menkes observed that akathisia is often miscoded in antidepressant clinical trials as "agitation, emotional lability, and hyperkinesis (overactivity)".[5] The study further points out that misdiagnosis of akathisia as simple motor restlessness occurs, but that this is more properly classed as dyskinesia. Healy, et al., further show links between antidepressant-induced akathisia and violence, including suicide, as akathisia can "exacerbate psychopathology." The study goes on to state that there is extensive clinical evidence correlating akathisia with SSRI use, showing that approximately ten times as many patients on SSRIs as those on placebos showed symptoms severe enough to drop out of a trial (5.0% compared to 0.5%).




    Treatment

    Treatment includes the discontinuation or reduction of dose of the causative agent.

    The most common treatment for antipsychotic akathisia is the anticholinergic medication benztropine (Cogentin). But since benztropine is for extrapyramidal side effects such as muscle spasms, muscle stiffness and tremors it is not effective in treating akathisia which is not a true extrapyramidal side effect. Other anticholinergic medications such as diphenhydramine may also be used in the treatment of akathisia.

    Akathisia can be reduced by administering other drugs, though effectiveness can vary with more severe cases resistant to most drug treatment. Benzodiazepines like clonazepam (Klonopin) are effective. Some consider the drug of choice for the treatment of akathisia to be beta-blockers such as propranolol (Inderal) or metoprolol. The antihistamine cyproheptadine is also effective, though with shorter effect than beta blockers.

    One study showed that vitamin B6 is effective for the treatment of neuroleptic-induced akathisia.[9]

    Raneados on
  • KarpmanKarpman Registered User regular
    edited March 2008
    Can I get propranalol any other way tahn by perescription? It's also called . propranolol hydrochloride. I;ms eriously considerign suicide here.

    I have famuli watahcin me, so I will be ok.


    I just want it to stop.. Im so tired and can;'t stop moving

    Karpman on
  • KarpmanKarpman Registered User regular
    edited March 2008
    I finally went to the emergency room again and got on the right drug, I think. I'm feeling more in control now. Also, I think I can spell again. Go ahead and close this thread.

    Karpman on
This discussion has been closed.