This is the largest thing. Imagine organ transplants that don't need anti-rejection pills, steroids, and a gamut of antibiotics/antivirals. Of course I'm sure drug companies will be sad, but fuck those guys.
If they're smart, they'll branch out into the equipment & chemicals needed to perform organ cloning. Medical devices & surgery supplies are a huge business, they just face different business challenges so pharma companies have to be careful reaching into that space.
(Can you tell I used to work for a pharma strategic consulting company? )
Cloning isn't the current best hope of transplant organs, due to requiring the organ to be built from scratch (which requires the support systems in place in order to the specific bits you want made). Answer probably lies in cell localisation - if you have the structure in place (so basically strip a pigs heart down to the basic skeleton) and then put stem cells in it, they realise they are in a heart (and whereabouts) and start developing to 'plug the holes'. Whether it works with a whole organ I'm not so sure, not heard anything lately (but then not looked).
Won't the mammoth just die in a couple of days anyway? Doesn't anything that is cloned die within a couple of days?
......no?
Edit: Clones are, however, destined to die before the thing they are cloned from.
Stupid Telomeres.
Humans have telomerases, the reactivation of them is one of the required steps for cancers - they're only active in embryos. Basically, your cloned embryo will repair and extend the telomeres of the original donor as part of it's development. Don't forget - the DNA that made you is copied from something that has been replicated billions of times, it's a strand that's been implanted from your adult parents into a cloning cell and then repaired.
I hope I can eventually clone myself and then put my consciousness into my new body!
Why clone yourself? Clone some good looking, genetically awesome person and have your consciousness put in that new body.
If he's going to transplant his brain into the new body then he better be sure of his brain not being rejected due to a nasty immune system.
Brain and bone marrow transplant? Job done.
Seems like you'd need to do a lot more of that. Or at least some sort of plasmapheresis to remove the current antibodies in the blood.
I'd have thought it unlikely they'd have antibodies against the donor, especially since we're talking clones. They don't hand around for long though and it's not hard to take out the cells that'll respond to or create them. We should probably focus our efforts on the brain transplant side, maybe practise with a few corpses first, electrical stimulation of the motor cortex of the brain should be a nice obvious sign that the connections have taken - if only there was some source that could provide the significant power we would need.
Dinosaurs are the one thing I wouldn't want to bring back - we'd be so disappointed with how they really look, and watching some sort of Doom Puffin slowly expire from lack of oxygen would just kill off the last of my childhood. Far better to try to correct the genes in chickens or ostriches, see how many of the dinosaur traits we can bring back.
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L Ron HowardThe duckMinnesotaRegistered Userregular
I'd have thought it unlikely they'd have antibodies against the donor, especially since we're talking clones. They don't hand around for long though and it's not hard to take out the cells that'll respond to or create them. We should probably focus our efforts on the brain transplant side, maybe practise with a few corpses first, electrical stimulation of the motor cortex of the brain should be a nice obvious sign that the connections have taken - if only there was some source that could provide the significant power we would need.
I think I've heard of this idea before. Can't quite put my finger on it, though.
There is no reason that - if we were able to do so - we shouldn't bring back Mammoths or extinct animals, or help the preservation of animals under the threat of extinction.
There is no reason that - if we were able to do so - we shouldn't bring back Mammoths or extinct animals, or help the preservation of animals under the threat of extinction.
Except, you know, ecological terrorism.
And; Cloning can't help a species that is near extinction.
There is no reason that - if we were able to do so - we shouldn't bring back Mammoths or extinct animals, or help the preservation of animals under the threat of extinction.
Except, you know, ecological terrorism.
And; Cloning can't help a species that is near extinction.
Modern cloning couldn't, but I mean, if the technology goes far enough that we can just poop a hundred blue whales a month out of the cloning vats then it might. Although, this would only help if the species had been destroyed by something which was at that point resolved.
We had a thread about that "First Synthetic Life" created thing a year or so ago, right?
I guess some guys kinda one-up'ed them a little while back.
They made some E. Coli that had non-natural occuring protiens in it and still survived.
Which, yeah, I guess could mean that cloning might some day be useful for species on the brink of extinction, because in theory we could give them genetic variation.
But then it isn't really cloning as much as synthesising life.
So, again, cloning can't help an near-extinct species.
We NEED to invest heavily in cloning cloning and myco-electric prosthesis in order to survive the shitstorm that'll occur when antibiotics and anti-necrotic/rejection drugs stop working.
Remember all of the shitty sci-fi villains based around this? Yeah, we're going to become the goddamned Phage if you don't do enough science.
First we need to outlaw feeding antibiotics to cattle as a growth accelerator on a global scale and prosecute abuses with an iron fist to slow the goddamm process down. Its stupidity in its purest form.
Arch is the resident biologist, but anti biotics can actually become viable again if not used much, as the immunities are shed as the bug is no longer exposed.
This all reminds me of Discovery's "Raising the Mammoth"
That was such a fucking let down. "Oh it got left in a storage place and the heat climbed up and the little guy rotted and ewww we're not cloning that shit" or something like that.
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This all reminds me of Discovery's "Raising the Mammoth"
That was such a fucking let down. "Oh it got left in a storage place and the heat climbed up and the little guy rotted and ewww we're not cloning that shit" or something like that.
Put that way, it sounds hilarious. Like, scientists being all prissy with their clone candidate samples.
Arch is the resident biologist, but anti biotics can actually become viable again if not used much, as the immunities are shed as the bug is no longer exposed.
Worth noting.
Unfortunately, it doesn't work exactly that way with many antibiotics because many of the drug resistance mutations confer resistance to groups of antibiotics so you have to stop using all of the related drugs for several decades before any of them can become effective again.
For instance, doctors don't prescribe penicillin very often any more but penicillin resistance is still very common because penicillin derivatives are still very commonly used.
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L Ron HowardThe duckMinnesotaRegistered Userregular
There is no reason that - if we were able to do so - we shouldn't bring back Mammoths or extinct animals, or help the preservation of animals under the threat of extinction.
Except, you know, ecological terrorism.
And; Cloning can't help a species that is near extinction.
Modern cloning couldn't, but I mean, if the technology goes far enough that we can just poop a hundred blue whales a month out of the cloning vats then it might. Although, this would only help if the species had been destroyed by something which was at that point resolved.
The other side of that is that if we can poop a hundred blue whales a month out of cloning vats, we won't actually need to keep blue whales alive as a species. If we ever develop a hankering for having some blue whales around, we could just make some.
There is no reason that - if we were able to do so - we shouldn't bring back Mammoths or extinct animals, or help the preservation of animals under the threat of extinction.
Except, you know, ecological terrorism.
And; Cloning can't help a species that is near extinction.
Modern cloning couldn't, but I mean, if the technology goes far enough that we can just poop a hundred blue whales a month out of the cloning vats then it might. Although, this would only help if the species had been destroyed by something which was at that point resolved.
The other side of that is that if we can poop a hundred blue whales a month out of cloning vats, we won't actually need to keep blue whales alive as a species. If we ever develop a hankering for having some blue whales around, we could just make some.
The ultimate designer safari holiday.
"Yeah, I'd like some Bengal tigers, a few Kudu, a leopard or two, whichever elephant that best matches my umbrella, and of course the most dangerous quarry of all... a t-rex with a gun."
There is no reason that - if we were able to do so - we shouldn't bring back Mammoths or extinct animals, or help the preservation of animals under the threat of extinction.
Except, you know, ecological terrorism.
And; Cloning can't help a species that is near extinction.
Modern cloning couldn't, but I mean, if the technology goes far enough that we can just poop a hundred blue whales a month out of the cloning vats then it might. Although, this would only help if the species had been destroyed by something which was at that point resolved.
The other side of that is that if we can poop a hundred blue whales a month out of cloning vats, we won't actually need to keep blue whales alive as a species. If we ever develop a hankering for having some blue whales around, we could just make some.
The problem with this is that Blue Whales have a lot of behaviors they need to learn. We saw something kinda similar with Elephants where too many of the older males were killed by poachers so the young males grew up without good role models and murdered rhinos. The last thing we need is a pod of young blue whales attacking boats.
Ooo! I was wondering how long it would be before they tried this. I don't mind resurrecting recently extinct animals, particularly those driven there by human hand. Chances are, the environments that they lived in could still handle them. That said, I don't know about introducing resurrected species to the wild until one is ABSOLUTELY sure. We have a terrible habit of throwing things into the wild that create terrible environmental problem later on.
Actually, the animal I wish they would resurrect is the Auroch. It's a kind of wild bull and was human kind's ancestral food source in Europe back in the stone age. The last one only went extinct cerca 1600. I think that would be our best bet.
I for one endorss cloning the raptors, I mean, hunting them would be the ultimate game
But wow, really, not to sound old but the things I've read about during the last decade makes me want to freeze myself so I can see the Wonders of the Future.
Ooo! I was wondering how long it would be before they tried this. I don't mind resurrecting recently extinct animals, particularly those driven there by human hand. Chances are, the environments that they lived in could still handle them. That said, I don't know about introducing resurrected species to the wild until one is ABSOLUTELY sure. We have a terrible habit of throwing things into the wild that create terrible environmental problem later on.
Actually, the animal I wish they would resurrect is the Auroch. It's a kind of wild bull and was human kind's ancestral food source in Europe back in the stone age. The last one only went extinct cerca 1600. I think that would be our best bet.
We still got photos of Tasmanian tigers. Australia has a lot of empty space. It would be a perfect breeding ground for all these kinds of resurrection experiments.
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Cloning isn't the current best hope of transplant organs, due to requiring the organ to be built from scratch (which requires the support systems in place in order to the specific bits you want made). Answer probably lies in cell localisation - if you have the structure in place (so basically strip a pigs heart down to the basic skeleton) and then put stem cells in it, they realise they are in a heart (and whereabouts) and start developing to 'plug the holes'. Whether it works with a whole organ I'm not so sure, not heard anything lately (but then not looked).
Humans have telomerases, the reactivation of them is one of the required steps for cancers - they're only active in embryos. Basically, your cloned embryo will repair and extend the telomeres of the original donor as part of it's development. Don't forget - the DNA that made you is copied from something that has been replicated billions of times, it's a strand that's been implanted from your adult parents into a cloning cell and then repaired.
If he's going to transplant his brain into the new body then he better be sure of his brain not being rejected due to a nasty immune system.
Brain and bone marrow transplant? Job done.
The two are one and the same ;-)
then maybe cloning extinct creatures is not exactly what you're after? Because they aren't exactly... new...
Seems like you'd need to do a lot more of that. Or at least some sort of plasmapheresis to remove the current antibodies in the blood.
I wonder if we could make new old veggies, though. Not as interesting as animals, but potentially just as tasty.
Does this strike you as the ideal place for a T-Rex?
I'd have thought it unlikely they'd have antibodies against the donor, especially since we're talking clones. They don't hand around for long though and it's not hard to take out the cells that'll respond to or create them. We should probably focus our efforts on the brain transplant side, maybe practise with a few corpses first, electrical stimulation of the motor cortex of the brain should be a nice obvious sign that the connections have taken - if only there was some source that could provide the significant power we would need.
Dinosaurs are the one thing I wouldn't want to bring back - we'd be so disappointed with how they really look, and watching some sort of Doom Puffin slowly expire from lack of oxygen would just kill off the last of my childhood. Far better to try to correct the genes in chickens or ostriches, see how many of the dinosaur traits we can bring back.
I think I've heard of this idea before. Can't quite put my finger on it, though.
Except, you know, ecological terrorism.
And; Cloning can't help a species that is near extinction.
Modern cloning couldn't, but I mean, if the technology goes far enough that we can just poop a hundred blue whales a month out of the cloning vats then it might. Although, this would only help if the species had been destroyed by something which was at that point resolved.
I guess some guys kinda one-up'ed them a little while back.
They made some E. Coli that had non-natural occuring protiens in it and still survived.
Which, yeah, I guess could mean that cloning might some day be useful for species on the brink of extinction, because in theory we could give them genetic variation.
But then it isn't really cloning as much as synthesising life.
So, again, cloning can't help an near-extinct species.
Let's be honest, that T-rex would be shot dead so fast..
Unless we gave THEM guns!
Seriously, heavily armed Dinosaurs is the one idea that cannot possibly go wrong.
Why I fear the ocean.
That's why I said the Dakotas.
At least there, there's less people. They still all got guns, but there's less of them.
Democrats Abroad! || Vote From Abroad
Mmmmm....toasty.
Remember all of the shitty sci-fi villains based around this? Yeah, we're going to become the goddamned Phage if you don't do enough science.
Or we die and cats take over the world.
Worth noting.
:x
I thought we were gonna clone up some Aurochs first, funding courtesy of Red Bull, so we could get us some supertaurine.
Wouldnt that basically doom the mammoth to dying from hypoxia?
Nobody will shatter the image of early man's history that I have going, so don't try
That was such a fucking let down. "Oh it got left in a storage place and the heat climbed up and the little guy rotted and ewww we're not cloning that shit" or something like that.
3DS FC: 4699-5714-8940 Playing Pokemon, add me! Ho, SATAN!
you forgot about the amulets
tell us about the amulets
Put that way, it sounds hilarious. Like, scientists being all prissy with their clone candidate samples.
Grow-ussss.
Unfortunately, it doesn't work exactly that way with many antibiotics because many of the drug resistance mutations confer resistance to groups of antibiotics so you have to stop using all of the related drugs for several decades before any of them can become effective again.
For instance, doctors don't prescribe penicillin very often any more but penicillin resistance is still very common because penicillin derivatives are still very commonly used.
Give the T-rexes some Sharks to ride too, while we're at it.
The other side of that is that if we can poop a hundred blue whales a month out of cloning vats, we won't actually need to keep blue whales alive as a species. If we ever develop a hankering for having some blue whales around, we could just make some.
The ultimate designer safari holiday.
"Yeah, I'd like some Bengal tigers, a few Kudu, a leopard or two, whichever elephant that best matches my umbrella, and of course the most dangerous quarry of all... a t-rex with a gun."
Actually, the animal I wish they would resurrect is the Auroch. It's a kind of wild bull and was human kind's ancestral food source in Europe back in the stone age. The last one only went extinct cerca 1600. I think that would be our best bet.
But wow, really, not to sound old but the things I've read about during the last decade makes me want to freeze myself so I can see the Wonders of the Future.
We still got photos of Tasmanian tigers. Australia has a lot of empty space. It would be a perfect breeding ground for all these kinds of resurrection experiments.