BroloBroseidonLord of the BroceanRegistered Userregular
edited February 2011
This Human Immunodeficiency Virus model summarizes the results from more then 100 latest scientific publications in the fields of virology, X-ray analysis and NMR spectroscopy. The depicted spatial configurations of 17 different viral and cellular proteins found in HIV particle are in strict accordance with known 3D-structures.
Viral membrane in the model includes 160 thousand lipid molecules of 8 different types in the proportion found in the HIV particle.
This model of HIV virion is put on the cover of the special issue of Nature Medicine (September 8, 2010) prepared by the Global HIV Vaccine Enterprise. In this release, the Enterprise publishes the strategic research plan to accelerate the development of vaccines against HIV (the «2010 Plan»).The 2010 Plan is developed by the Council of the Global HIV Vaccine Enterprise with the participation of hundreds of scientists, policy-makers, funders and advocates worldwide.
Human immunodeficiency virus (HIV) is a retrovirus, member of the lentivirus genus. HIV infects and destroys cells of the human immune system (CD4+ T-lymphocytes, macrophages and dendritic cells). The decrease of CD4+ T-lymphocytes level causes the development of acquired immunodeficiency syndrome (AIDS). There are two major species of HIV: HIV-1 and HIV-2, which is less common.
HIV virion is a roughly spherical particle with a diameter between 100 and 180 nm. Virion is surrounded by cell-derived lipid membrane containing surface proteins. Some of these proteins are products of viral genome (surface glycoprotein gp120/gp41) and others are captured from the host cell during viral budding (e.g. ICAM-1, HLA-DR1, CD55 and some others). The gp120/gp41 glycoprotein interacts with receptors on cell surface promoting fusion of virus and cell membranes. Other surface proteins found in HIV perform supporting functions.
Trimers of MA (p17) protein form a layer directly under the lipid membrane. Inside the HIV particle there is a cone-shaped capsid, composed of CA (p24) proteins. Capsid contains two copies of positive single-stranded viral RNA bound by NC (p7) protein and enzymes necessary for virus replication (reverse transcriptase and integrase).
The HIV genome is approximately 10000 nucleotides long and contains 9 genes, which encode 15 different proteins. The most important viral genes (open reading frames) are Gag, Pol and Env. Gag encodes the p55 protein, which is subsequently cut into structural proteins: MA, CA, NC and p6. Pol reading frame encodes integrase, protease, and reverse transcriptase. Env encodes the two subunits of the surface glycoprotein complex. Other genes (Tat, Rev, Vif, Vpr, Vpu and Nef) produce accessory proteins, which modulate host cell metabolism and facilitate different stages of HIV life cycle.
Tugboat is a design crush of mine. Friends and I brought them in for a gallery showing this past month and they were not only incredible in the print department, but we got good and drunk with them that night as well. Props all around.
More importantly, read the "about". Their process is insane.
Tugboat is a design crush of mine. Friends and I brought them in for a gallery showing this past month and they were not only incredible in the print department, but we got good and drunk with them that night as well. Props all around.
More importantly, read the "about". Their process is insane.
Their little print cart reminds me of a guy who would roll his pickup truck in front of a school or something loaded with his press and just start cranking out prints for people right there
Then there's burlesque which houses the wonderful Wes winship. He does pretty much all of arcade fire's tour posters and they are pretty much always awesome
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#pipeCocky Stride, Musky odoursPope of Chili TownRegistered Userregular
edited February 2011
My favourite illustrator is a guy from my home town called Monaux
His compositions are so amazingly balanced and his linework is so confident and I am in love with his script and style. Lots of his work would make amazing prints.
I emailed him a while ago to commission a tattoo design and he emailed me back, super humble and approachable and apologised that he probably wouldn't have the time unless I offered him more money than it was probably worth, but that I should give him the brief of my idea anyway and if he found inspiration some time he'd knock something out for free!
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Dear satan I wish for this or maybe some of this....oh and I'm a medium or a large.
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Dear satan I wish for this or maybe some of this....oh and I'm a medium or a large.
But man that table/sink/island is beautiful.
(NSFW for a couple of art boobs)
http://irinawerning.com/back-to-the-fut/back-to-the-future/
This is a photographer who takes a subject's favourite photograph of him or herself from the past and recreates it as accurately as possible
Pretty cool!
Need some stuff designed or printed? I can help with that.
hee hee hee
http://www.etsy.com/listing/65460668/whale-tissue-holder-cyan
Viral membrane in the model includes 160 thousand lipid molecules of 8 different types in the proportion found in the HIV particle.
This model of HIV virion is put on the cover of the special issue of Nature Medicine (September 8, 2010) prepared by the Global HIV Vaccine Enterprise. In this release, the Enterprise publishes the strategic research plan to accelerate the development of vaccines against HIV (the «2010 Plan»).The 2010 Plan is developed by the Council of the Global HIV Vaccine Enterprise with the participation of hundreds of scientists, policy-makers, funders and advocates worldwide.
Human immunodeficiency virus (HIV) is a retrovirus, member of the lentivirus genus. HIV infects and destroys cells of the human immune system (CD4+ T-lymphocytes, macrophages and dendritic cells). The decrease of CD4+ T-lymphocytes level causes the development of acquired immunodeficiency syndrome (AIDS). There are two major species of HIV: HIV-1 and HIV-2, which is less common.
HIV virion is a roughly spherical particle with a diameter between 100 and 180 nm. Virion is surrounded by cell-derived lipid membrane containing surface proteins. Some of these proteins are products of viral genome (surface glycoprotein gp120/gp41) and others are captured from the host cell during viral budding (e.g. ICAM-1, HLA-DR1, CD55 and some others). The gp120/gp41 glycoprotein interacts with receptors on cell surface promoting fusion of virus and cell membranes. Other surface proteins found in HIV perform supporting functions.
Trimers of MA (p17) protein form a layer directly under the lipid membrane. Inside the HIV particle there is a cone-shaped capsid, composed of CA (p24) proteins. Capsid contains two copies of positive single-stranded viral RNA bound by NC (p7) protein and enzymes necessary for virus replication (reverse transcriptase and integrase).
The HIV genome is approximately 10000 nucleotides long and contains 9 genes, which encode 15 different proteins. The most important viral genes (open reading frames) are Gag, Pol and Env. Gag encodes the p55 protein, which is subsequently cut into structural proteins: MA, CA, NC and p6. Pol reading frame encodes integrase, protease, and reverse transcriptase. Env encodes the two subunits of the surface glycoprotein complex. Other genes (Tat, Rev, Vif, Vpr, Vpu and Nef) produce accessory proteins, which modulate host cell metabolism and facilitate different stages of HIV life cycle.
That is really neat.
My guess is its actually a hard plastic.
Was this inspired by ZeFrank? It reminds me of Young Me/Now Me.
it's a g-g-g-g-ghost chair!
Need some stuff designed or printed? I can help with that.
Satans..... hints.....
sometimes it's okay to get a font boner
I figure of course you guys want to know what I'm buying i mean WHY WOULDN'T YOU
Tonight it is a print from Physical Fiction, which makes awesome pixel art letterpress prints using legos.
If you're starved for things to buy surf Gigposters for a bit and I'm sure you'll find something you love
Need some stuff designed or printed? I can help with that.
That site looks good pipe, a few others are omgposters and 20x200, which puts out new art prints every week starting at $20.
I love prints
http://www.tugboatprintshop.com/
Tugboat is a design crush of mine. Friends and I brought them in for a gallery showing this past month and they were not only incredible in the print department, but we got good and drunk with them that night as well. Props all around.
More importantly, read the "about". Their process is insane.
Another one:
http://theheadsofstate.com/
Again, very very cool guys doing some great work. Highly recommend it.
My mouth is literally agape
Need some stuff designed or printed? I can help with that.
"Proposed and rejected logo for coffee/bookstore"
who in the shit would reject that? that is a stunning logo.
Need some stuff designed or printed? I can help with that.
Their little print cart reminds me of a guy who would roll his pickup truck in front of a school or something loaded with his press and just start cranking out prints for people right there
Wish i could remember his name
NSFW for more artboobs
His compositions are so amazingly balanced and his linework is so confident and I am in love with his script and style. Lots of his work would make amazing prints.
I emailed him a while ago to commission a tattoo design and he emailed me back, super humble and approachable and apologised that he probably wouldn't have the time unless I offered him more money than it was probably worth, but that I should give him the brief of my idea anyway and if he found inspiration some time he'd knock something out for free!
Need some stuff designed or printed? I can help with that.
Satans..... hints.....
http://yvettesbridalformal.com/index.htm
hey satan...: thinkgeek amazon My post |
avant garde?
Yeah, that would make a super good tattoo also!
it's real
about how sometimes hierarchy is so bad that you're looking at a design full of words and your brain simply can't read any of them
that website is like that
Need some stuff designed or printed? I can help with that.